Amphetamines are stimulant drugs that are used to increase alertness, focus and energy. They are commonly prescribed to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy but are also used illicitly as recreational drugs due to their euphoric effects. Common street names for amphetamines include speed, uppers, phets and bennies.
When you take amphetamines, they increase the release of dopamine, a neurotransmitter that is responsible for feelings of pleasure and reward. This results in an intense rush of euphoria, energy and confidence which make amphetamines popular party drugs. However, amphetamine abuse also increases heart rate, blood pressure and breathing, all of which can lead to dangerous health consequences.
Some common amphetamines which can and do commonly lead to addiction include:
- Adderall – A prescription medication, is a combination of amphetamine and dextroamphetamine, used to treat narcolepsy and ADHD.
- Dexedrine – Another prescription medication that comprises dextroamphetamine and is also used to treat people with ADHD and narcolepsy.
- Ritalin – Used to treat ADHD and narcolepsy, contains methylphenidate, a CNS stimulant that is similar to amphetamines.
- Vyvanse – A prescription medication used to treat binge eating disorder and ADHD which contains lisdexamfetamine, a prodrug that is metabolised into dextroamphetamine in the body.
How does amphetamine addiction develop?
Amphetamine addiction can develop in two ways – through prescription drug use or recreational abuse. Prescription drug addiction occurs when someone takes drugs in a manner other than prescribed, such as taking higher doses or taking the drug more frequently. Recreational abuse occurs when someone takes amphetamines for non-medical purposes, such as to get high or to enhance performance.
Amphetamine tolerance
Either way, if you use amphetamines excessively or for a long time (though some people can become addicted after only mild, short-term use) your brain will try to compensate for the changes by reducing the number of receptors for those neurotransmitters. This means you need more and more of the stimulant to get the same effects as before, a process known as tolerance.
Amphetamine dependence
At the same time, your brain starts to adapt to having high levels of certain neurotransmitters by reducing its own production. This means that if you stop taking the stimulant suddenly, you can experience withdrawal symptoms because your brain is not used to functioning without it. This is physical dependence and once it has developed, amphetamine addiction is likely to follow.